CD8 anticorps
Aperçu rapide pour CD8 anticorps (ABIN114167)
Antigène
Voir toutes CD8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- This clone recognises the murine CD8 cell surface antigen, expressed by a subset of T lymphocytes.
-
Purification
- Affinity chromatography on Protein G
-
Isotype
- IgG2b
-
-
-
-
Indications d'application
-
Flow cytometry (1: 50 - 1: 100, use 10 μL to label 10^6 cells in 100 μL. Method sheets areavailable on request). Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline pH 7.4, containing 0.09 % Sodium Azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- CD8
-
Autre désignation
- CD8
-
Sujet
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
-
ID gène
- 12525
-
NCBI Accession
- NP_001074579
-
UniProt
- P01731
Antigène
-